{"id":11606,"date":"2016-09-27T14:13:49","date_gmt":"2016-09-27T17:13:49","guid":{"rendered":"https:\/\/www.infobioquimica.com\/new\/?p=11606"},"modified":"2016-09-27T14:13:49","modified_gmt":"2016-09-27T17:13:49","slug":"gonorrhea-may-become-resistant-to-all-antibiotics-sooner-than-anticipated","status":"publish","type":"post","link":"https:\/\/www.infobioquimica.com\/new\/2016\/09\/27\/gonorrhea-may-become-resistant-to-all-antibiotics-sooner-than-anticipated\/","title":{"rendered":"Gonorrhea May Become Resistant to All Antibiotics Sooner Than Anticipated"},"content":{"rendered":"

Experts have been worried<\/a> for a while\u00a0that time is running out for the last working cures for gonorrhea infections. <\/strong>Some revealed there may be even less time left on the clock than had been previously thought.<\/p>\n

Scientists from the Centers for Disease Control\u00a0and Prevention\u00a0<\/strong>and Hawaii\u2019s department of health reported a cluster of cases of gonorrhea in that state in which\u00a0the Neisseria gonorrhoeae<\/em> bacteria<\/strong> showed\u00a0high-level resistance to one of the drugs, azithromycin, as well as reduced susceptibility to the second drug, ceftriaxone.<\/p>\n

The two drugs are used in combination, a move experts hope will slow down the bacteria\u2019s relentless march through the antibiotic medicine cabinet.<\/p>\n

There had already been signs<\/a> that the bacteria, which have vanquished multiple other antibiotics, were starting to be able to evade these ones as well. Since 2005, there have been four isolated cases reported in which\u00a0the Neisseria gonorrhoeae<\/em> bacteria had reduced susceptibility to both drugs. But this is the first time a cluster of such cases has been seen in the US.<\/p>\n

\u201cOur last line of defense against gonorrhea is weakening,\u201d Dr.\u00a0Jonathan Mermin, director of CDC\u2019s National Center for HIV\/AIDS, Viral Hepatitis, STD, and TB Prevention said in a statement.\u00a0\u201cIf resistance continues to increase and spread, current treatment will ultimately fail and 800,000 Americans a year will be at risk for untreatable gonorrhea.\u201d<\/p>\n

Untreated gonorrhea<\/strong> can cause chronic pelvic pain, infertility<\/strong>, and ectopic pregnancies<\/strong>\u2014in which\u00a0a fertilized egg starts to develop in a fallopian\u00a0tube, not the uterus. Ectopic pregnancies can be life-threatening.<\/p>\n

The cluster of cases described by Dr. Alan Katz of Hawaii\u2019s state board of health involved six men and a woman, but was in fact undoubtedly larger. They did not have sex with each other, so must have been infected by other people.\u00a0Katz said the seven people reported a total of eight sexual partners. Four of the eight agreed to be tested, but none was\u00a0infected.<\/p>\n

Analysis of the genetic sequences showed they were closely related, Katz said.<\/p>\n

All seven people were cured of their infections. But it seems only a matter of time before treatment failures occur. Earlier this year doctors from Britain reported that a man infected with gonorrhea was not cured by his first course of antibiotics, though follow-up treatment three months later did quell the infection.<\/p>\n

If this combination of drugs fail, there is no other treatment option currently available. Several experimental\u00a0antibiotics are in development and one has recently been shown to be effective in a Phase 2 trial. But it is still likely years away from hitting the market.<\/p>\n

Source:<\/strong> Scientific American<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

Experts have been worried for a while\u00a0that time is running out for the last working cures for gonorrhea infections. Some revealed there may be even less time left on the clock than had been previously thought. Scientists from the Centers for Disease Control\u00a0and Prevention\u00a0and Hawaii\u2019s department of health reported a cluster of cases of gonorrhea […]<\/p>\n","protected":false},"author":2620,"featured_media":11607,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"twitterCardType":"summary_large_image","cardImageID":0,"cardImage":"","cardTitle":"","cardDesc":"","cardImageAlt":"","cardPlayer":"","cardPlayerWidth":0,"cardPlayerHeight":0,"cardPlayerStream":"","cardPlayerCodec":"","footnotes":""},"categories":[655],"tags":[15519,15507,7921,15509,4541,15517,15503,15501,15513,15505,12362,15511,15521,15515,4427],"class_list":["post-11606","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-noticias-ingles","tag-alan-katz","tag-azithromycin","tag-bacteria-en","tag-ceftriaxone","tag-centers-for-disease-control-and-prevention-en","tag-chronic-pelvic-pain","tag-gonorrhea","tag-gonorrhea-infections","tag-hivaids","tag-infections","tag-infertility","tag-jonathan-mermin","tag-neisseria-gonorrhoeae-en","tag-std","tag-viral-hepatitis"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.infobioquimica.com\/new\/wp-json\/wp\/v2\/posts\/11606","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.infobioquimica.com\/new\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.infobioquimica.com\/new\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.infobioquimica.com\/new\/wp-json\/wp\/v2\/users\/2620"}],"replies":[{"embeddable":true,"href":"https:\/\/www.infobioquimica.com\/new\/wp-json\/wp\/v2\/comments?post=11606"}],"version-history":[{"count":1,"href":"https:\/\/www.infobioquimica.com\/new\/wp-json\/wp\/v2\/posts\/11606\/revisions"}],"predecessor-version":[{"id":11608,"href":"https:\/\/www.infobioquimica.com\/new\/wp-json\/wp\/v2\/posts\/11606\/revisions\/11608"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.infobioquimica.com\/new\/wp-json\/wp\/v2\/media\/11607"}],"wp:attachment":[{"href":"https:\/\/www.infobioquimica.com\/new\/wp-json\/wp\/v2\/media?parent=11606"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.infobioquimica.com\/new\/wp-json\/wp\/v2\/categories?post=11606"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.infobioquimica.com\/new\/wp-json\/wp\/v2\/tags?post=11606"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}